CJC-1295 DAC Dosage, Protocol, and GH Optimization Guide (Long-Acting GHRH)
CJC-1295 DAC
CJC-1295 DAC is a long-acting GHRH analog designed to increase growth hormone (GH) and IGF-1 levels over several days. The DAC (Drug Affinity Complex) binds to albumin, extending its half-life to approximately 6–8 days and allowing infrequent dosing.
How CJC-1295 DAC Works
GHRH Activation → GH Release ↑ → IGF-1 ↑ → Fat Loss + Recovery + Anabolism
CJC-1295 DAC stimulates the pituitary gland to release GH while remaining active in circulation for several days. Unlike NO DAC, which creates short pulses, DAC provides sustained GH elevation while still allowing natural pulsatility.
Long-acting GHRH analog with extended half-life (~6–8 days)
Promotes sustained GH elevation rather than short pulses
Less frequent dosing compared to NO DAC versions
Often used for convenience and stable IGF-1 elevation
CJC-1295 DAC Protocol
5 mg vial + 2.0 mL BAC Water → 1 unit = 25 mcg → Long-Acting GH Support
Standard Setup
Vial
5 mg
Water
2.0 mL bacteriostatic water
Concentration
2.5 mg/mL
Conversion
1 unit = 25 mcg
Weeks 1–2
Start Phase
Dose300 mcg
Units12 units
Volume0.12 mL
Weekly Total600 mcg
Weeks 3–4
Build Phase
Dose500 mcg
Units20 units
Volume0.20 mL
Weekly Total1000 mcg
Weeks 5–6
Peak Phase
Dose750 mcg
Units30 units
Volume0.30 mL
Weekly Total1500 mcg
Weeks 7–12
Maintain Phase
Dose1000 mcg
Units40 units
Volume0.40 mL
Weekly Total2000 mcg
Protocol Details
FrequencyTwice weekly (every 3–4 days)
AlternativeOnce weekly (advanced)
Cycle Length8–12 weeks
Optional ExtensionUp to 16 weeks
Simple structure
Because CJC-1295 DAC stays active for several days, consistent weekly scheduling matters more than daily timing precision.
Because CJC-1295 DAC stays active for several days, consistent weekly scheduling matters more than daily timing precision.
How to Use (Timing & Injection)
Injection TypeSubcutaneous
TimingEvening preferred (optional)
ScheduleFixed days (ex: Mon / Thu)
Use StyleLong-acting GH support
When & Where to Inject
Subcutaneous injection
Abdomen, thigh, or upper arm
Inject on consistent days weekly
Rotate injection sites regularly
Timing Notes
Evening dosing is common but not required
Consistency matters more than exact time of day
Long half-life removes need for daily timing precision
Reconstitution & Dosing (5 mg Vial)
Vial5 mg
Water2.0 mL bacteriostatic
Concentration2.5 mg/mL
Conversion1 unit = 25 mcg
Dose Reference
12 units = 300 mcg
20 units = 500 mcg
30 units = 750 mcg
40 units = 1000 mcg
Reconstitution Steps
Draw 2.0 mL bacteriostatic water
Inject slowly down vial wall
Gently swirl, do not shake
Allow powder to fully dissolve
Label with mix date
Refrigerate immediately
Storage & Shelf Life
Storage & Shelf Life
Lyophilized (Unmixed)
Short-term: refrigerate at 2–8°C
Long-term: freeze at −20°C / −4°F
Refrigerated shelf life: ~12–24 months
Frozen shelf life: ~2–3 years
Keep sealed, dry, and protected from light
Avoid repeated temperature changes
Reconstituted (Mixed)
Refrigerate at 2–8°C
Use within 2–4 weeks
Do not freeze after mixing
Discard if cloudy or degraded
Cycle Length & Time Between Cycles
Sustained GH Phase → Break → Reassess IGF-1 → Repeat if Needed
Cycle Structure
Cycle Length8–12 weeks
Optional ExtensionUp to 16 weeks
GoalSustained GH + IGF-1 elevation
Time Between Cycles
Break4–6 weeks
Helps maintain GH receptor sensitivity
Allows hormone levels to normalize
Improves long-term effectiveness
Why cycle?
Long-acting GH stimulation can lead to diminishing returns over time. Cycling helps maintain responsiveness and reduce unnecessary hormone elevation.
Long-acting GH stimulation can lead to diminishing returns over time. Cycling helps maintain responsiveness and reduce unnecessary hormone elevation.
Monitoring During Use
IGF-1 levels (primary biomarker)
Body composition changes
Sleep quality and recovery
Water retention or edema
Benefits
Sustained GH and IGF-1 elevation
Improved recovery and muscle repair
Enhanced fat metabolism
Increased protein synthesis
Convenient dosing schedule
Potential Side Effects
Water retention
Mild flushing
Injection site irritation
Headache (rare)
Stacking Strategies
GH Support → Recovery → Fat Loss Optimization
Fat Loss: CJC-1295 DAC + AOD-9604
Recovery: CJC-1295 DAC + BPC-157
Advanced: Combine with GHRPs (research-based)
Important Notes
Long half-life requires consistent scheduling
Less precise than NO DAC for timing control
May cause more water retention than short-acting peptides
Provides smoother GH elevation vs pulsatile spikes
Important Disclaimer
CJC-1295 DAC is not FDA-approved. This content is for educational purposes only.
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