CJC-1295 (NO DAC) + Ipamorelin Dosage, Protocol, and Reconstitution Guide
CJC-1295 (NO DAC) + Ipamorelin
This combination pairs a growth hormone releasing hormone peptide with a growth hormone secretagogue to create a stronger natural GH pulse. It is one of the most commonly discussed GH support combinations for recovery, body composition, sleep, and lean mass support.
How It Works
GHRH Signal (CJC-1295) + Ghrelin Signal (Ipamorelin) → GH Pulse ↑↑ → IGF-1 ↑ → Recovery + Fat Loss + Lean Mass Support
CJC-1295 (NO DAC) stimulates the pituitary through GHRH pathways, while Ipamorelin activates the ghrelin receptor. Together, they create a stronger pulsatile growth hormone response than either peptide alone.
Blended Vial Protocol (Simple)
5 mg CJC-1295 + 5 mg Ipamorelin → 3.0 mL BAC Water → 1 unit = 16.7 mcg of each peptide
Blended Vial Setup
Blend5 mg CJC-1295 + 5 mg Ipamorelin
Water3.0 mL
Concentration1.67 mg/mL each peptide
Conversion1 unit = 16.7 mcg CJC-1295 + 16.7 mcg Ipamorelin
Combined1 unit = about 33 mcg total
Weeks 1–2
Loading
Dose100 mcg of each peptide
Combined Total200 mcg total
Units6 units total
Volume0.06 mL
Weeks 3–4
Build
Dose150 mcg of each peptide
Combined Total300 mcg total
Units9 units total
Volume0.09 mL
Weeks 5–8
Peak
Dose200 mcg of each peptide
Combined Total400 mcg total
Units12 units total
Volume0.12 mL
Weeks 9–12
Maintenance
Dose250 mcg of each peptide
Combined Total500 mcg total
Units15 units total
Volume0.15 mL
Why use blended?
Simple Option
This is the simplest option. Both peptides are delivered together in one syringe with one draw and one injection.
Best For
Great for convenience, easy math, and a more beginner-friendly structure.
Separate Vials Protocol (Advanced)
CJC-1295 = GHRH Support → Ipamorelin = Ghrelin Receptor Support → Flexible Timing with the Same Target Doses
Separate Vials Setup
Based on 5 mg vials for each peptide
CJC-12955 mg vial + 3.0 mL BAC water
Ipamorelin5 mg vial + 3.0 mL BAC water
CJC Conversion1 unit = 16.7 mcg
Ipamorelin Conversion1 unit = 16.7 mcg
Weeks 1–2
Loading
CJC-12956 units (100 mcg)
Ipamorelin6 units (100 mcg)
Total Drawn12 units total
Combined Total200 mcg total
Volume0.12 mL
Weeks 3–4
Build
CJC-12959 units (150 mcg)
Ipamorelin9 units (150 mcg)
Total Drawn18 units total
Combined Total300 mcg total
Volume0.18 mL
Weeks 5–8
Peak
CJC-129512 units (200 mcg)
Ipamorelin12 units (200 mcg)
Total Drawn24 units total
Combined Total400 mcg total
Volume0.24 mL
Weeks 9–12
Maintenance
CJC-129515 units (250 mcg)
Ipamorelin15 units (250 mcg)
Total Drawn30 units total
Combined Total500 mcg total
Volume0.30 mL
Why use separate vials?
More Control
This setup gives you more control. You can still match the same standard doses, but you can also change the schedule later if you want to adjust one peptide without changing the other.
Best For
Useful when you want flexibility and future control.
Advanced Protocol (Morning + Night)
Split Dosing → More Frequent GH Pulses → Better Mimic of Natural Rhythms
Weeks 1–2
Intro
Morning50 mcg CJC + 50 mcg Ipamorelin
Night100 mcg CJC + 100 mcg Ipamorelin
Daily Total150 mcg each
Weeks 3–4
Build
Morning100 mcg CJC + 100 mcg Ipamorelin
Night100 mcg CJC + 100 mcg Ipamorelin
Daily Total200 mcg each
Weeks 5–8
Peak
Morning100 mcg CJC + 100 mcg Ipamorelin
Night150 mcg CJC + 150 mcg Ipamorelin
Daily Total250 mcg each
Weeks 9–12
Maintenance
Morning150 mcg CJC + 150 mcg Ipamorelin
Night150 mcg CJC + 150 mcg Ipamorelin
Daily Total300 mcg each
Why split dosing?
Natural Rhythm Support
Morning and night dosing may better mimic natural GH pulsatility and can increase total daily GH signaling compared to one bedtime-only dose.
Best For
More advanced GH support protocols that require better meal timing discipline.
How to Use CJC-1295 (NO DAC) + Ipamorelin
Cycle Length8–12 weeks
Break Between Cycles2–4 weeks off
Injection TypeSubcutaneous
Use StyleBlended, separate, or split dosing
Best Time to Take
Most commonly used 30–60 minutes before bed
Split-dose protocols often use a fasted morning dose plus a bedtime dose
Consistency matters more than chasing perfect timing
Where to Inject
Abdomen, thigh, or upper arm
Rotate injection sites regularly
Separate-vial users often draw both into one syringe
Food Timing (Why It Matters)
Before InjectionAvoid eating for 2–3 hours before
After InjectionWait 20–30 minutes before eating
WhyInsulin and elevated blood sugar can reduce the GH pulse
CJC-1295 (NO DAC) and Ipamorelin are commonly used in a fasted state because growth hormone release is stronger when insulin is low.
Eating carbohydrates or a full meal too close to your injection may blunt the intended GH response.
A common simple rule is: inject when fasted, then wait about 20–30 minutes before eating.
When to Use
During recovery-focused phases
During body composition support phases
When better sleep and GH support are a main goal
As a structured GH support protocol rather than casual nonstop use
Reconstitution & Dosing
Blended Vial Reconstitution
Blend5 mg CJC-1295 + 5 mg Ipamorelin
Water3.0 mL total
Concentration1.67 mg/mL each
Conversion1 unit = 16.7 mcg CJC + 16.7 mcg Ipamorelin
Steps
Draw 3.0 mL bacteriostatic water
Inject slowly down the vial wall
Gently swirl, do not shake
Allow powder to fully dissolve before use
Refrigerate after reconstitution
Use within about 4 weeks after mixing
Separate Vials Reconstitution
CJC-12955 mg vial
Ipamorelin5 mg vial
Water3.0 mL into each vial
CJC Conversion1 unit = 16.7 mcg
Ipamorelin Conversion1 unit = 16.7 mcg
Steps
Draw 3.0 mL bacteriostatic water into the CJC-1295 vial
Draw 3.0 mL bacteriostatic water into the Ipamorelin vial
Inject slowly down each vial wall
Gently swirl each vial, do not shake
Refrigerate both vials after mixing
Use within about 4 weeks after reconstitution
Blended vs Separate (Which Should You Use?)
Blended Vial
Best for simplicity and convenience
Both peptides follow the same timing and dose progression
Easy math and beginner-friendly structure
Separate Vials
Best if you want more control later
Lets you adjust one peptide independently if needed
Useful if your source sells them separately
Simple takeaway:
Choose blended if you want simplicity. Choose separate if you want flexibility and future control.
Choose blended if you want simplicity. Choose separate if you want flexibility and future control.
Storage & Shelf Life
Storage & Shelf Life
Lyophilized (unmixed)
Refrigerated (2–8°C): ~12–24 months
Frozen (−20°C): up to ~2–3 years
Reconstituted (mixed)
Refrigerated (2–8°C): ~30 days typical use window
Do not freeze after mixing
Blended vs Separate Storage
Blended Vial
Both peptides share the same solution, so storage and stability are tied together.
Separate Vials
Separate vials can give you slightly more flexibility with handling and preservation.
Best Practice
Handling
Keep vials cold and protected from light.
Temperature
Avoid repeated temperature changes.
Visual Check
If solution becomes cloudy, discolored, or has particles, discard.
Time Between Cycles
Standard Time Between Cycles
Cycle Length8–12 weeks
Time Off2–4 weeks
Why take a break?
CJC-1295 (NO DAC) + Ipamorelin is usually run in defined GH support phases rather than continuously. Taking time off helps reassess response and keeps the protocol more purpose-driven.
CJC-1295 (NO DAC) + Ipamorelin is usually run in defined GH support phases rather than continuously. Taking time off helps reassess response and keeps the protocol more purpose-driven.
When to Stop Sooner
Sleep, recovery, or body composition benefits feel flat
The main goal phase has ended
Meal timing discipline is slipping and the protocol is no longer being used as intended
Monitoring During Use
Sleep quality and deep sleep response
Recovery and soreness
Body composition changes
IGF-1 levels on longer cycles
Benefits
Synergistic growth hormone release
Improved recovery and tissue repair
Enhanced fat metabolism
Lean muscle support
Better sleep quality
Potential Side Effects
Mild injection site irritation
Headache (rare)
Water retention
Temporary hunger increase
Stacking Strategies
GH Pulse ↑ → IGF-1 ↑ → Recovery + Body Composition Support
Recovery: Add BPC-157
Advanced: Add IGF-1 LR3
Body Composition: Pair with disciplined sleep, training, and nutrition
Important Notes
One of the most commonly discussed GH peptide combinations
Blended and separate setups produce the same peptide amounts
Separate vials require drawing from two sources, so total handled volume is higher
100 mcg each = 200 mcg combined total
Consistency matters more than aggressive dosing
Important Disclaimer
CJC-1295 (NO DAC) and Ipamorelin are not FDA-approved and are intended for research purposes only.
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